Medications

Medication information sheets:

Amitriptyline

Amitriptyline is a medicine that is used to help manage chronic (long term) pain. It is often recommended in particular when people have been having a lot of trouble sleeping due to the impact of the pain. It is also used in higher doses to treat depression.

Azathioprine

Azathioprine is a medicine used to treat certain childhood rheumatic conditions (diseases which may affect kidneys, joints, muscles, skin, gut or eyes). This can include lupus (also known as SLE), inflammatory bowel disease, uveitis and scleroderma. People who have had organ transplants also use it. Azathioprine is a medicine that works by suppressing your immune system. It reduces the damage done by inflammation, rather than just reducing pain.

Cyclophosphamide

Cyclophosphamide is a medicine used to treat severe inflammatory diseases (diseases which may affect kidneys, blood vessels, joints, muscles, skin, gut or eyes). This can include complicated lupus (also known as SLE), vasculitis, uveitis and scleroderma. It is also used to treat certain cancers.

Hydroxychloroquine

Hydroxycholoroquine is a medicine used to treat certain childhood rheumatic conditions (diseases which may affect joints, muscles, skin or eyes). It is most commonly used to treat lupus (also known as SLE). Hydroxycholoroquine was originally designed to treat malaria.

Leflunomide

Leflunomide is a medicine which works by reducing the activity of the immune system. Rather than just relieving pain it acts to reduce the damage to the joints. It belongs to the group of medicines called disease modifying antirheumatic drugs (DMARDs). Other DMARDs commonly used in Juvenile Idiopathic Arthritis are methotrexate, hydroxychloroquine, sulfasalazine.

Methotrexate

Methotrexate is a medicine used to treat certain childhood rheumatic conditions (diseases which may affect joints, muscles, skin or eyes). These include juvenile arthritis (JIA), lupus (also known as SLE), uveitis, dermatomyositis and scleroderma.

Mycophenolate mofetil

Mycophenolate mofetil is usually a medicine used to treat certain childhood rheumatic conditions (diseases which may affect kidneys, joints, muscles, skin, gut or eyes). This can include lupus (also known as SLE), inflammatory bowel disease, uveitis and scleroderma. It is also used in patients who have had transplants.

NSAIDs – Non steroidal anti-inflammatory drugs

Non steroidal anti-inflammatory drugs (NSAIDs) are medicines commonly used to treat painful swollen joints. They are not steroids but are effective in reducing pain and stiffness. These medicines are often used when your child is initially diagnosed with arthritis because they quickly control the pain and inflammation. However, usually other drugs need to be added over time in order to further improve your child’s condition.

Steroids

Steroids are hormones that occur naturally in the body. We use them as medicines to treat certain childhood rheumatic conditions (diseases which may affect joints, muscles, bones, skin or eyes). This can include juvenile arthritis (JIA), lupus (also known as SLE), uveitis, dermatomyositis and scleroderma.

Sulfasalazine

Sulfasalazine is a medicine used to treat certain childhood rheumatic conditions (diseases which may affect joints, muscles, skin or eyes). This can include juvenile arthritis (JIA) and inflammatory bowel disease.

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