These conditions are very rare and are more likely to happen in younger children from the first year of life onwards. Every few weeks they may have fevers and other symptoms (rash, joint pain, tummy pains, etc.) for a few days for no apparent reasons. The kids are often misdiagnosed as having “infection” and given many courses of antibiotics without any good benefit. There may be genetic testing available for them but often it take a very long time to diagnose them.